The pathogenesis of inflammatory bowel disease is orchestrated by specific subsets of cytokine-secreting T cells. The interleukin 9–producing subset of helper T cells contributes to the pathogenesis of inflammatory bowel disease in part by disrupting intestinal barrier function and impairing tissue-repair mechanisms.
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Hufford, M., Kaplan, M. A gut reaction to IL-9. Nat Immunol 15, 599–600 (2014). https://doi.org/10.1038/ni.2916
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DOI: https://doi.org/10.1038/ni.2916
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