Inflammasomes are signaling platforms of the innate immune system that activate proinflammatory cytokines after microbial pathogens are sensed or sterile danger is detected. The kinases Syk and Jnk control inflammasome activation by mediating phosphorylation of the inflammasome adaptor ASC.
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Neumann, K., Ruland, J. Kinases conquer the inflammasomes. Nat Immunol 14, 1207–1208 (2013). https://doi.org/10.1038/ni.2763
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DOI: https://doi.org/10.1038/ni.2763
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