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Casting new light on the TCR

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Dynamic imaging portrays intraepidermal T cells as truly autoreactive, constitutively transmitting signals from a putative ligand expressed by normal epithelial cells.

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Figure 1: Postulated underappreciated parallels between the DETCs TCR and KIRs.

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Authors and Affiliations

  1. Cancer Research UK and Peter Gorer Department of Immunobiology, Adrian Hayday is with the London Research Institute, King's College London, London, UK.,

    Adrian Hayday

  2. Robert Tigelaar is in the Department of Dermatology, Yale University, New Haven, Connecticut, USA.,

    Robert Tigelaar

Authors
  1. Adrian Hayday
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  2. Robert Tigelaar
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Correspondence to Adrian Hayday.

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The authors declare no competing financial interests.

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Hayday, A., Tigelaar, R. Casting new light on the TCR. Nat Immunol 13, 209–211 (2012). https://doi.org/10.1038/ni.2243

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