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Provocative exhibits at the Seventeen Gallery

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Two studies identify a tissue-autonomous innate immune mechanism whereby infection provokes epithelial cells to produce IL-17C that engages an epithelial receptor composed of IL-17RA and IL-17RE chains, which promotes host defense and immune activation.

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Figure 1: A revised view of the IL-17 portfolio.

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Authors and Affiliations

  1. Mahima Swamy and Adrian Hayday are in the Peter Gorer Department of Immunobiology, King's College, Guy's Hospital, London, UK, and London Research Institute, Cancer Research UK, London, UK.,

    Mahima Swamy & Adrian Hayday

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  1. Mahima Swamy
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  2. Adrian Hayday
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Correspondence to Adrian Hayday.

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The authors declare no competing financial interests.

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Swamy, M., Hayday, A. Provocative exhibits at the Seventeen Gallery. Nat Immunol 12, 1131–1133 (2011). https://doi.org/10.1038/ni.2164

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