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Flippin' lipids

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B cell generation is disturbed in four newly identified mouse mutants bearing X-linked mutations in the gene encoding the ATPase ATP11C. These findings suggest that the distribution of membrane phospholipids confers a yet-to-be delineated developmental signal.

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Figure 1: Flippases, floppases and PS.

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Authors and Affiliations

  1. Marcus R. Clark is in the Department of Medicine, Section of Rheumatology and Gwen Knapp Center for Lupus Research, University of Chicago, Chicago, Illinois, USA.,

    Marcus R Clark

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  1. Marcus R Clark
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Correspondence to Marcus R Clark.

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Clark, M. Flippin' lipids. Nat Immunol 12, 373–375 (2011). https://doi.org/10.1038/ni.2024

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