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Copy number variation and antigenic repertoire

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The success of bone marrow transplantation depends on whether transplanted immune cells respond in graft versus host disease. A new study identifies a common gene deletion that is associated with immune response following transplantation.

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Figure 1: Graft-versus-host disease (GVHD) is associated with mismatch for UGT2B17.

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  1. John A.L. Armour is at the School of Biology and Institute of Genetics, University of Nottingham, Queen's Medical Centre, Nottingham, UK.,

    John A L Armour

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  1. John A L Armour
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Correspondence to John A L Armour.

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Armour, J. Copy number variation and antigenic repertoire. Nat Genet 41, 1263–1264 (2009). https://doi.org/10.1038/ng1209-1263

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