Embryonic stem (ES) cells undergo rapid cell division without compromising their ability to differentiate into virtually all cell types. Using ES cells deficient for a microRNA biogenesis factor, Dgcr8, a new report uncovers the importance of specific microRNAs in the ES cell cycle transition from G1 to S phase.
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Kim, V. Cell cycle micromanagement in embryonic stem cells. Nat Genet 40, 1391–1392 (2008). https://doi.org/10.1038/ng1208-1391
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DOI: https://doi.org/10.1038/ng1208-1391
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