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Not so lost in the genetic crowd

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Two new studies report improved statistics to predict whether an individual participated in a genome-wide association study based on aggregate allele or genotype frequency information. They demonstrate that it may be possible to release summary statistics for a subset of genetic markers in a study while maintaining individual privacy.

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Figure 1: Power to detect individual membership in a genome-wide study depends on the number of markers and the sample size.

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Authors and Affiliations

  1. Scripps Health and the Department of Molecular and Experimental Medicine, Nicholas J. Schork and Vikas Bansal are at the Scripps Translational Science Institute, The Scripps Research Institute, La Jolla, California, USA.,

    Nicholas J Schork & Vikas Bansal

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  1. Nicholas J Schork
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  2. Vikas Bansal
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Correspondence to Nicholas J Schork.

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Schork, N., Bansal, V. Not so lost in the genetic crowd. Nat Genet 41, 1163–1164 (2009). https://doi.org/10.1038/ng1109-1163

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