A new study presents a comprehensive global analysis of the evolution of segmental duplications in the human genome. The authors identify the origin of ancestral duplication loci, regions of clustered duplicons, and evidence supporting a punctuated model of evolution.
This is a preview of subscription content, log in via an institution to check access.
References
She, X. et al. Nature 431, 927–930 (2004).
Jiang, Z. et al. Nat. Genet. 39, 1361–1368 (2007).
Pevzner, P.A., Tang, H. & Tesler, G. Genome Res. 14, 1786–1796 (2004).
Olson, M.V. & Varki, A. Nat. Rev. Genet. 4, 20–28 (2003).
McCarroll, S.A. & Altshuler, D.M. Nat. Genet. 39 (Suppl.), S37–S42 (2007).
Conrad, D.F. & Hurles, M.E. Nat. Genet. 39 (Suppl.), S30–S36 (2007).
Levy, S. et al. PLoS Biol. 5, e254 (2007).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Birney, E. Double Dutch for duplications. Nat Genet 39, 1303–1304 (2007). https://doi.org/10.1038/ng1107-1303
Issue Date:
DOI: https://doi.org/10.1038/ng1107-1303
- Springer Nature America, Inc.