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A gene harvest revealing the archeology and complexity of human disease

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Abstract

An inflection point in genetics has been reached and was witnessed at the Genomics of Common Diseases meeting (http://www.nature.com/ng/meetings/genomics) co-sponsored by the Wellcome Trust, held at the Wellcome Trust Hinxton Conference Centre July 7–10, 2007 and co-organized by Tim Aitman, David Altshuler and Eddy Rubin.

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Figure 1: Gene effect size in common diseases.
Figure 2: A quantile-quantile plot showing the distribution of observed χ2 statistics in a meta-analysis of 3,200 individuals with Crohn's disease (cases) and 4,800 controls.

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Authors and Affiliations

  1. Enrico Petretto is at the Faculty of Medicine, Imperial College, London W12 0NN, UK. enrico.petretto@csc.mrc.ac.uk.,

    Enrico Petretto

  2. Edison T. Liu is at the Genome Institute of Singapore, 138672 Singapore.,

    Edison T Liu

  3. Timothy J. Aitman is at the MRC Clinical Sciences Centre, London, W12 0NN, UK. ,

    Timothy J Aitman

Authors
  1. Enrico Petretto
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  2. Edison T Liu
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  3. Timothy J Aitman
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Petretto, E., Liu, E. & Aitman, T. A gene harvest revealing the archeology and complexity of human disease. Nat Genet 39, 1299–1301 (2007). https://doi.org/10.1038/ng1107-1299

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