The recently completed International HapMap Project has provided detailed information about patterns of genetic variation in four different population samples. Two new studies show that the patterns of variation documented in the HapMap can be applied to other human populations, suggesting it is time to establish a standardized platform for all whole-genome association studies.
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References
Wade, N. New York Times 30 October 2002.
Hinds, D.A. et al. Science 307, 1072–1079 (2005).
de Bakker, P.I. et al. Nat. Genet. 37, 1217–1223 (2005).
Montpetit, A. et al. PLoS Genet. 2, e27 (2006).
Mueller, J.C. et al. Am. J. Hum. Genet. 76, 387–398 (2005).
De Bakker P.I. et al. Nat. Genet. 38, 1298–1303 (2006).
Conrad, D.F., et al. Nat. Genet. 38, 1251–1260 (2006).
Ahmadi, K.R. et al. Nat Genet. 37, 84–89 (2005).
International HapMap Consortium. Nature 437, 1299–1320 (2005).
Haines, J.L. et al. Science 308, 419–421 (2005).
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Need, A., Goldstein, D. Genome-wide tagging for everyone. Nat Genet 38, 1227–1228 (2006). https://doi.org/10.1038/ng1106-1227
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DOI: https://doi.org/10.1038/ng1106-1227
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