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The NCBI dbGaP database of genotypes and phenotypes

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The National Center for Biotechnology Information has created the dbGaP public repository for individual-level phenotype, exposure, genotype and sequence data and the associations between them. dbGaP assigns stable, unique identifiers to studies and subsets of information from those studies, including documents, individual phenotypic variables, tables of trait data, sets of genotype data, computed phenotype-genotype associations, and groups of study subjects who have given similar consents for use of their data.

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Figure 1: Accession numbers in dbGaP are created separately for a study and its subordinate objects — phenotype variables, phenotype trait tables, documents and genotype datasets – prefixed phs, phv, pht, phd and phg, respectively.

References

  1. The GAIN Collaborative Research Group. Nat. Genet. 39, 1045–1051 (2007).

  2. Lowrance, W.W. & Collins, F.S. ETHICS: identifiability in genomic research. Science 317, 600–602 (2007).

    Article  CAS  PubMed  Google Scholar 

  3. Harold, E.R. XML Bible 2nd edn. (Hungry Minds, Indianapolis, Indiana, USA, 2001).

    Google Scholar 

  4. Bray, T., Paoli, J., Sperberg-McQueen, C.M., Maler, E. & Yergeau, F. Extensible Markup Language (XML) 1.0 4th edn. (World Wide Web Consortium (W3C), 2006) <http://www.w3.org/TR/REC-xml/>.

    Google Scholar 

  5. Clayton, D.G. et al. Nat. Genet. 37, 1243–1246 (2005).

    Article  CAS  PubMed  Google Scholar 

  6. Devlin, B. & Roeder, K. Biometrics 55, 997–1004 (1999).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

Thanks to T. Manolio, J. Coleman, F Collins and C. O'Donnell for useful comments and discussion. This research was supported by the Intramural Research Program of the US National Institutes of Health, National Library of Medicine.

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Authors and Affiliations

  1. National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, 20892-6510, Maryland, USA

    Matthew D Mailman, Michael Feolo, Yumi Jin, Masato Kimura, Kimberly Tryka, Rinat Bagoutdinov, Luning Hao, Anne Kiang, Justin Paschall, Lon Phan, Natalia Popova, Stephanie Pretel, Lora Ziyabari, Moira Lee, Yu Shao, Zhen Y Wang, Karl Sirotkin, Minghong Ward, Michael Kholodov, Kerry Zbicz, Jeffrey Beck, Michael Kimelman, Sergey Shevelev, Don Preuss, Eugene Yaschenko, Alan Graeff, James Ostell & Stephen T Sherry

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  1. Matthew D Mailman
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  2. Michael Feolo
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  16. Zhen Y Wang
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  17. Karl Sirotkin
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  18. Minghong Ward
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  20. Kerry Zbicz
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  21. Jeffrey Beck
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  23. Sergey Shevelev
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  24. Don Preuss
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  25. Eugene Yaschenko
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  26. Alan Graeff
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  27. James Ostell
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  28. Stephen T Sherry
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Corresponding author

Correspondence to Stephen T Sherry.

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Mailman, M., Feolo, M., Jin, Y. et al. The NCBI dbGaP database of genotypes and phenotypes. Nat Genet 39, 1181–1186 (2007). https://doi.org/10.1038/ng1007-1181

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