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Tiling DNA microarrays for fly genome cartography

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Full-genome tiling arrays provide powerful biological evidence to support gene predictions and suggest the need for new and improved annotations. New studies using tiling arrays of the Drosophila melanogaster genome show that 85% of the fly genome is transcribed and processed into mature transcripts, representing 30% of the fly genome.

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Figure 1: Screen shots from the Affymetrix Integrated Genome Browser web interface.

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Oliver, B. Tiling DNA microarrays for fly genome cartography. Nat Genet 38, 1101–1102 (2006). https://doi.org/10.1038/ng1006-1101

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