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Lymph makes you fat

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A new study of mice lacking Prox1, a gene required for the formation of lymphatic endothelial cells, unveils a link between lymph fluid and fat deposition. These findings bring the lymphatic vascular system into the focus of obesity research.

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Figure 1: Defects in lymphatic vasculature promote obesity.

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Authors and Affiliations

  1. the Center for Transgene Technology and Gene Therapy, KULeuven, Flanders Interuniversitary Institute for Biotechnology, Campus Gasthuisberg, Herestraat 49, Leuven, B-3000, Belgium

    Martin Schneider, Edward M Conway & Peter Carmeliet

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  1. Martin Schneider
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  2. Edward M Conway
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  3. Peter Carmeliet
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Schneider, M., Conway, E. & Carmeliet, P. Lymph makes you fat. Nat Genet 37, 1023–1024 (2005). https://doi.org/10.1038/ng1005-1023

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