Skip to main content
SpringerLink
Log in

Psychiatric genetics gets a boost

  • News & Views
  • Published:

From Nature Genetics

View current issue Submit your manuscript

Defining the molecular nature of the genetic risk of psychiatric disorders has been notoriously difficult. Now, a flurry of genome-wide association studies for schizophrenia and bipolar disorder provides preliminary evidence for replicated signals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Characteristics of variants across the allelic spectrum.

References

  1. Chanock, S.J. & Hunter, D.J. Nature 452, 537–538 (2008).

    Article  CAS  PubMed  Google Scholar 

  2. Ferreira, M.A.R. et al. Nat. Genet. 40, 1056–1058 (2008).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. O'Donovan, M.C. et al. Nat. Genet. 40, 1053–1055 (2008).

    Article  CAS  PubMed  Google Scholar 

  4. Ioannidis, J.P., Patsopoulos, N.A. & Evangelou, E. PLoS ONE 2, e841 (2007).

    Article  PubMed  PubMed Central  Google Scholar 

  5. Wang, W.Y., Barratt, B.J., Clayton, D.G. & Todd, J.A. Nat. Rev. Genet. 6, 109–118 (2005).

    Article  CAS  PubMed  Google Scholar 

  6. Reich, D.E. & Lander, E.S. Trends Genet. 17, 502–510 (2001).

    Article  CAS  PubMed  Google Scholar 

  7. Sebat, J. et al. Science 316, 445–449 (2007).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Walsh, T. et al. Science 320, 539–543 (2008).

    Article  CAS  PubMed  Google Scholar 

  9. Xu, B. et al. Nat. Genet. 40, 880–885 (2008).

    Article  CAS  PubMed  Google Scholar 

  10. Roy, M.A., Walsh, D. & Kendler, K.S. Acta Psychiatr. Scand. 93, 224–234 (1996).

    Article  CAS  PubMed  Google Scholar 

  11. Stefansson, H. et al. Nature advance online publication, 10.1038/nature07229 (30 July 2008).

  12. The International Schizophrenia Consortium. Nature advance online publication, 10.1038/nature07239 (30 July 2008).

  13. Bassett, A.S., Chow, E.W. & Weksberg, R. Am. J. Med. Genet. 97, 45–51 (2000).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Kendler, K.S. & Diehl, S.R. Schizophr. Bull. 19, 261–285 (1993).

    Article  CAS  PubMed  Google Scholar 

  15. Hemminki, K., Forsti, A. & Bermejo, J.L. PLoS ONE 3, e2504 (2008).

    Article  PubMed  PubMed Central  Google Scholar 

  16. Sullivan, P.F., Kendler, K.S. & Neale, M.C. Arch. Gen. Psychiatry 60, 1187–1192 (2003).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Brien P. Riley and Kenneth S. Kendler are at the Virginia Institute for Psychiatric and Behavioral Genetics and the Departments of Psychiatry and Human and Molecular Genetics, Brion S. Maher, Virginia Commonwealth University School of Medicine, Richmond, Virginia 23298, USA. kendler@vcu.edu,

    Brion S Maher, Brien P Riley & Kenneth S Kendler

Authors
  1. Brion S Maher
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Brien P Riley
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kenneth S Kendler
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Maher, B., Riley, B. & Kendler, K. Psychiatric genetics gets a boost. Nat Genet 40, 1042–1044 (2008). https://doi.org/10.1038/ng0908-1042

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng0908-1042

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation