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RNA polymerase IV and transcriptional silencing

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RNA-based silencing mechanisms suppress gene expression through the sequence-specific activity of small RNAs. New studies in plants now identify atypical RNA polymerases that promote and maintain transcriptional silencing.

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Figure 1: Alternative models for the maintenance of siRNA-directed TGS.

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Vaucheret, H. RNA polymerase IV and transcriptional silencing. Nat Genet 37, 659–660 (2005). https://doi.org/10.1038/ng0705-659

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