Skip to main content
SpringerLink
Log in

A nuclear address with influence

  • News & Views
  • Published:

From Nature Genetics

View current issue Submit your manuscript

The spatial organization of the interphase nucleus is related to the differentiation state of the cell and has a role in establishing tissue-specific patterns of gene expression. Investigation of a tissue-specific nuclear protein has identified a new mechanism of cell-specific gene regulation that links nuclear architecture, chromatin structure and gene transcription.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Brown, K.E. et al. Cell 91, 845–854 (1997).

    Article  CAS  PubMed  Google Scholar 

  2. Cremer, T. & Cremer, C. Nat. Rev. Genet. 2, 292–301 (2001).

    Article  CAS  PubMed  Google Scholar 

  3. Parada, L. & Misteli, T. Trends Cell Biol. 12, 425–432 (2002).

    Article  CAS  PubMed  Google Scholar 

  4. Volpi, E.V. et al. J. Cell Sci. 113 Pt 9, 1565–1576 (2000).

    CAS  PubMed  Google Scholar 

  5. Mahy, N.L., Perry, P.E., Gilchrist, S., Baldock, R.A. & Bickmore, W.A. J. Cell Biol. 157, 579–589 (2002).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Hancock, R. Chromosoma 109, 219–225 (2000).

    Article  CAS  PubMed  Google Scholar 

  7. Forrester, W.C., Fernandez, L.A. & Grosschedl, R. Genes Dev. 13, 3003–3014 (1999).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Forrester, W.C., van Genderen, C., Jenuwein, T. & Grosschedl, R. Science 265, 1221–1225 (1994).

    Article  CAS  PubMed  Google Scholar 

  9. Jenuwein, T. et al. Nature 385, 269–272 (1997).

    Article  CAS  PubMed  Google Scholar 

  10. Bode, J. et al. Science 255, 195–197 (1992).

    Article  CAS  PubMed  Google Scholar 

  11. Kohwi-Shigematsu, T. & Kohwi, Y. Biochemistry 29, 9551–9560 (1990).

    Article  CAS  PubMed  Google Scholar 

  12. Dickinson, L.A., Joh, T., Kohwi, Y. & Kohwi-Shigematsu, T. Cell 70, 631–645 (1992).

    Article  CAS  PubMed  Google Scholar 

  13. Cai, S., Han, H.-J. & Kohwi-Shigematsu, T. Nat. Genet. 34, 42–51 (2003).

    Article  CAS  PubMed  Google Scholar 

  14. Wilsker, D., Patsialou, A., Dallas, P.B. & Moran, E. Cell Growth Differ. 13, 95–106 (2002).

    CAS  PubMed  Google Scholar 

  15. Alvarez, J.D. et al. Genes Dev. 14, 521–535 (2000).

    CAS  PubMed  PubMed Central  Google Scholar 

  16. Yasui, D., Miyano, M., Cai, S., Varga-Weisz, P. & Kohwi-Shigematsu, T. Nature 419, 641–645 (2002).

    Article  CAS  PubMed  Google Scholar 

  17. Jenuwein, T. & Allis, C.D. Science 293, 1074–1080 (2001).

    Article  CAS  PubMed  Google Scholar 

  18. Berger, S.L. Curr. Opin. Genet. Dev. 12, 142–148 (2002).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Molecular Bioscience, John Curtin School of Medical Research, Australian National University, Canberra, 2601, ACT, Australia

    M. Frances Shannon

Authors
  1. M. Frances Shannon
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Shannon, M. A nuclear address with influence. Nat Genet 34, 4–6 (2003). https://doi.org/10.1038/ng0503-4

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/ng0503-4

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation