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MicroRNAs in facial development

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Cranial neural crest cell migration is a prerequisite for normal craniofacial morphogenesis in animals. A new study shows that the movement of a specific subset of cranial neural crest cells is exquisitely sensitive to concentrations of a microRNA that targets platelet-derived growth factor receptor alpha mRNA.

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Figure 1: Mirn140 attenuates Pdgfra signaling in palatal precursors.

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Authors and Affiliations

  1. David E. Clouthier is in the Department of Craniofacial Biology, University of Colorado Denver, Aurora, Colorado 80045, USA. david.clouthier@uchsc.edu,

    David E Clouthier

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  1. David E Clouthier
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Clouthier, D. MicroRNAs in facial development. Nat Genet 40, 268–269 (2008). https://doi.org/10.1038/ng0308-268

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  • DOI: https://doi.org/10.1038/ng0308-268

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