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An unsettling picture emerges from population genomic studies of Plasmodium vivax

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Two new studies confirm that Plasmodium vivax populations are more diverse than Plasmodium falciparum and identify signs of recent selection at many loci, including those for drug resistance. P. vivax shows a trend of regional adaptations that poses challenges to global efforts to control and eliminate this major cause of relapsing malaria.

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References

  1. World Health Organization. World Malaria Report 2015 (World Health Organization, 2015).

  2. Price, R.N. et al. Am. J. Trop. Med. Hyg. 77 (Suppl.), 79–87 (2007).

    Article  Google Scholar 

  3. Neafsey, D.E. et al. Nat. Genet. 44, 1046–1050 (2012).

    Article  CAS  Google Scholar 

  4. Carlton, J.M. et al. Nature 455, 757–763 (2008).

    Article  CAS  Google Scholar 

  5. Chan, E.R. et al. PLoS Negl. Trop. Dis. 6, e1811 (2012).

    Article  CAS  Google Scholar 

  6. Winter, D.J. et al. PLoS Negl. Trop. Dis. 9, e0004252 (2015).

    Article  Google Scholar 

  7. Hupalo, D.N. et al. Nat. Genet. 48, 953–958 (2016).

  8. Pearson, R.D. et al. Nat. Genet. 48, 959–964 (2016).

  9. Auburn, S. et al. PLoS One 6, e22213 (2011).

    Article  CAS  Google Scholar 

  10. Melnikov, A. et al. Genome Biol. 12, R73 (2011).

    Article  CAS  Google Scholar 

  11. Tachibana, S. et al. Nat. Genet. 44, 1051–1055 (2012).

    Article  CAS  Google Scholar 

  12. Miller, L.H., Mason, S.J., Clyde, D.F. & McGinniss, M.H. N. Engl. J. Med. 295, 302–304 (1976).

    Article  CAS  Google Scholar 

  13. Kwiatkowski, D.P. Am. J. Hum. Genet. 77, 171–192 (2005).

    Article  CAS  Google Scholar 

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Correspondence to Jessica C Kissinger.

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Kissinger, J. An unsettling picture emerges from population genomic studies of Plasmodium vivax. Nat Genet 48, 825–826 (2016). https://doi.org/10.1038/ng.3630

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