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The genomic landscape of adult T cell leukemia/lymphoma

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Adult T cell leukemia/lymphoma (ATL) is a neoplasm linked to human T-lymphotropic virus type-1 (HTLV-1) infection and is refractory to current combination chemotherapy. A large genomic and transcriptomic study of ATL now provides detailed insight into the molecular lesions implicated in the development of this T cell malignancy.

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Figure 1: Pathways altered in ATL.

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Authors and Affiliations

  1. Carmen Vicente and Jan Cools are at the Center for Human Genetics, KU Leuven, Leuven, Belgium, and at the Center for the Biology of Disease, VIB, Leuven, Belgium.,

    Carmen Vicente & Jan Cools

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  1. Carmen Vicente
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  2. Jan Cools
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Correspondence to Jan Cools.

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The authors declare no competing financial interests.

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Vicente, C., Cools, J. The genomic landscape of adult T cell leukemia/lymphoma. Nat Genet 47, 1226–1227 (2015). https://doi.org/10.1038/ng.3428

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