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Counting copy number and calories

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Copy number variation (CNV) at several genomic loci has been associated with different human traits and diseases, but in many cases the findings could not be replicated. A new study provides insights into the degree of variation present at the amylase locus and calls into question a previous association between amylase copy number and body mass index.

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Figure 1: Amylase locus variation.

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Authors and Affiliations

  1. Department of Human Genetics, Stefan White is at the Leiden Genome Technology Center, Leiden University Medical Center, Leiden, the Netherlands.,

    Stefan White

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  1. Stefan White
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Correspondence to Stefan White.

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White, S. Counting copy number and calories. Nat Genet 47, 852–853 (2015). https://doi.org/10.1038/ng.3365

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