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Exploring new models of easiRNA biogenesis

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Although silent transposons in plants can be reactivated by stress or during development, their potential deleterious effects are prevented by transposon-derived epigenetically activated small interfering RNAs (easiRNAs). A new study shows how serendipitous interactions between reactivated transposons and endogenous microRNAs might initiate easiRNA biogenesis, establishing an unexpected link between these two classes of silencing small RNAs.

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Figure 1: Models for easiRNA biogenesis triggered by miRNAs.

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Authors and Affiliations

  1. Alexis Sarazin and Olivier Voinnet are in the Department of Biology at the Swiss Federal Institute of Technology Zürich, Zürich, Switzerland.,

    Alexis Sarazin & Olivier Voinnet

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  1. Alexis Sarazin
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  2. Olivier Voinnet
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Correspondence to Olivier Voinnet.

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The authors declare no competing financial interests.

Supplementary information

Supplementary Figure 1

Anticipated molecular requirements for microRNA-triggered easiRNA biogenesis. (PDF 245 kb)

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Sarazin, A., Voinnet, O. Exploring new models of easiRNA biogenesis. Nat Genet 46, 530–531 (2014). https://doi.org/10.1038/ng.2993

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