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A clear picture of renal cell carcinoma

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Two recent studies describe the largest molecular profiling analyses to date of clear-cell renal cell carcinoma (ccRCC) and report remarkably similar findings. The recurrent pathway alterations identified in these studies open new avenues for therapeutic advances in this chemotherapy- and radiation-resistant disease.

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Figure 1: Integrated analyses of hundreds of ccRCC tumor samples identify recurrent pathway alterations.

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Authors and Affiliations

  1. A. Ari Hakimi, Can G. Pham and James J. Hsieh are at the Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.,

    A Ari Hakimi, Can G Pham & James J Hsieh

Authors
  1. A Ari Hakimi
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  2. Can G Pham
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  3. James J Hsieh
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Correspondence to James J Hsieh.

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The authors declare no competing financial interests.

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Hakimi, A., Pham, C. & Hsieh, J. A clear picture of renal cell carcinoma. Nat Genet 45, 849–850 (2013). https://doi.org/10.1038/ng.2708

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