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Turning of COGS moves forward findings for hormonally mediated cancers

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Abstract

The large-scale Collaborative Oncological Gene-environment Study (COGS) presents new findings that further characterize the genetic bases of breast, ovarian and prostate cancers. We summarize and provide insights into this collection of papers from COGS and discuss the implications of the results and future directions for such efforts.

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Figure 1
Figure 2: Pleiotropy among different cancers detected by COGS and previous association studies.

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Acknowledgements

This work is supported by US NIH grants R01 CA088164, U01 CA127298 and U19 CA148537.

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Authors and Affiliations

  1. Division of Research, Kaiser Permanente Northern California, Oakland, California, USA

    Lori C Sakoda & Eric Jorgenson

  2. Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

    Lori C Sakoda

  3. Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA

    John S Witte

  4. Institute for Human Genetics, University of California, San Francisco, San Francisco, California, USA

    John S Witte

Authors
  1. Lori C Sakoda
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  2. Eric Jorgenson
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  3. John S Witte
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Correspondence to John S Witte.

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The authors declare no competing financial interests.

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Sakoda, L., Jorgenson, E. & Witte, J. Turning of COGS moves forward findings for hormonally mediated cancers. Nat Genet 45, 345–348 (2013). https://doi.org/10.1038/ng.2587

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