David Adam pieces together the recent gains in our understanding of pain.
References
Caterina, M.J. et al. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389, 816 - 824 1997.
Caterina, M.J. et al. Impaired nociception and pain sensation in mice lacking the capsaicin receptor. Science 288, 306 - 313 2000.
Davis, J.B. et al. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 405, 183 - 187 2000.
Cockayne, D.A. et al. Urinary bladder hyporeflexia and reduced pain-related behaviour in P2X3-deficient mice. Nature 407, 1011 - 1015 2000.
Souslova, V. et al. Warm-coding deficits and aberrant inflammatory pain in mice lacking P2X3 receptors. Nature 407, 1015 - 1017 2000.
Rights and permissions
About this article
Cite this article
Adam, D. Solving the pain puzzle. Nature (2000). https://doi.org/10.1038/news001026-11
Published:
DOI: https://doi.org/10.1038/news001026-11
- Springer Nature Limited