Gene-therapy enzymes make unpredicted errors

Techniques show mistakes of 'highly specific' molecular tools.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Gabriel, R. et al. Nature Biotechnol. http://dx.doi.org/10.1038/nbt.1948 (2011).
Pattanayak, V., Ramirez, C. L., Joung, J. K. & Liu, D. R. Nature Methods http://dx.doi.org/10.1038/nmeth.1670 (2011).
Hacein-Bey-Abina, S. et al. Science 302, 415-419 (2003).
Article ADS CAS Google Scholar

Authors

Heidi Ledford
View author publications
You can also search for this author in PubMed Google Scholar

Ledford, H. Gene-therapy enzymes make unpredicted errors. Nature (2011). https://doi.org/10.1038/news.2011.461