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Does on-demand vardenafil improve erectile function recovery after radical prostatectomy?

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Abstract

The randomized, placebo-controlled trial reported by Montorsi and colleagues attempted to determine if nightly vardenafil was more effective than on-demand drug in restoring erectile function after radical prostatectomy. No significant difference in outcomes was found between the study groups at 11 or 13 months after surgery. The study, however, had enough methodological flaws to prevent any definitive conclusions from being drawn. The authors' conclusion that the data support a shift towards on-demand phosphodiesterase 5 inhibitor use after radical prostatectomy is not supported by the data.

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References

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Author notes

  1. Memorial Sloan–Kettering Cancer Center, 353 East 68th Street, New York, NY 10021, USA mulhalj1@mskcc.org

Authors and Affiliations

  1. JP Mulhall is Director of Sexual and Reproductive Medicine, Urology Service, Memorial Sloan–Kettering Cancer Center, New York, NY, USA.,

    John P Mulhall

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  1. John P Mulhall
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The author declares no competing financial interests.

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Mulhall, J. Does on-demand vardenafil improve erectile function recovery after radical prostatectomy?. Nat Rev Urol 6, 14–15 (2009). https://doi.org/10.1038/ncpuro1271

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  • DOI: https://doi.org/10.1038/ncpuro1271

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