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Risk stratification in acute decompensated heart failure: the role of cardiac troponin

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Abstract

Cardiac troponins provide important prognostic information in patients with acute decompensated heart failure. In a large study by the ADHERE Investigators, 6.2% of 67,924 patients with acute decompensated heart failure were positive for cardiac troponin; these individuals had lower blood pressure and lower ejection fraction than those who were negative for troponin. The study revealed that in-hospital mortality was significantly higher for troponin-positive patients than for troponin-negative individuals (8.0% vs 2.7%; P<0.001). Future studies need to define which treatment changes could improve outcome in troponin-positive patients with acute decompensated heart failure.

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Author notes

  1. Department of Internal Medicine, University Hospital Basel, Petersgraben 4, CH-4031 Basel, Switzerland chmueller@uhbs.ch

Authors and Affiliations

  1. C Mueller is Professor of Medicine at the University of Basel and Deputy Head of the Division of Internal Medicine at the University Hospital Basel, Basel, Switzerland.,

    Christian Mueller

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  1. Christian Mueller
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The author declares no competing financial interests.

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Mueller, C. Risk stratification in acute decompensated heart failure: the role of cardiac troponin. Nat Rev Cardiol 5, 680–681 (2008). https://doi.org/10.1038/ncpcardio1342

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  • DOI: https://doi.org/10.1038/ncpcardio1342

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