Identification of the monocarboxylate transporter 1 as a target of a new class of immunosuppressants shows that aerobic glycolysis and lactate release are essential for the proliferation of activated lymphocytes.
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Bröer, S. Lactate transportation is required for lymphocyte activation. Nat Chem Biol 1, 356–357 (2005). https://doi.org/10.1038/nchembio1205-356
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DOI: https://doi.org/10.1038/nchembio1205-356
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