Nitrite is an inorganic anion essential in cell signaling and vascular biology. A new study shows that the multicopper oxidase ceruloplasmin is critical for maintaining plasma nitrite, revealing a new link between copper and nitric oxide homeostasis.
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Samuel, T., Gitlin, J. Copper and nitric oxide meet in the plasma. Nat Chem Biol 2, 452–453 (2006). https://doi.org/10.1038/nchembio0906-452
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DOI: https://doi.org/10.1038/nchembio0906-452
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