A chemical-genetic study indicates that modulation of neurotransmitter signaling affects the self-renewal capacity of neural stem cells in culture. Although the mechanisms of action are not resolved, the research points to a potential therapeutic target class for treatment of brain tumors.
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Mercola, M. Chemical probes of neural stem cell self-renewal. Nat Chem Biol 3, 246–247 (2007). https://doi.org/10.1038/nchembio0507-246
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DOI: https://doi.org/10.1038/nchembio0507-246
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