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Chemical probes of neural stem cell self-renewal

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A chemical-genetic study indicates that modulation of neurotransmitter signaling affects the self-renewal capacity of neural stem cells in culture. Although the mechanisms of action are not resolved, the research points to a potential therapeutic target class for treatment of brain tumors.

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Figure 1: Neurotransmitter action on stem cells.

Katie Ris

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Mercola, M. Chemical probes of neural stem cell self-renewal. Nat Chem Biol 3, 246–247 (2007). https://doi.org/10.1038/nchembio0507-246

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  • DOI: https://doi.org/10.1038/nchembio0507-246

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