Small-molecule library screening identifies simple imitators of the cellular signaling events that normally guide formation of the pancreas and its insulin-secreting beta cells, further enabling detailed analysis in vitro, or eventual diabetes therapies via large-scale differentiation of human stem cells.
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Katie Vicari
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Yang, YP., Wright, C. Chemicals turn human embryonic stem cells towards beta cells. Nat Chem Biol 5, 195–196 (2009). https://doi.org/10.1038/nchembio0409-195
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DOI: https://doi.org/10.1038/nchembio0409-195
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