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Small-molecule switch for zebrafish gene expression

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The zebrafish is a highly promising model system for vertebrate genetics study, but the temporal control of gene expression has remained underdeveloped. A new chemical genetic system using a small-molecule switch for protein synthesis promises to increase the usefulness of the zebrafish as a vertebrate model system.

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Figure 1: Spatial control of gene expression by a small-molecule switch in zebrafish.

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Authors and Affiliations

  1. Young-Tae Chang is in the Department of Chemistry, New York University, New York, New York 10003, USA. yt.chang@nyu.edu,

    Young-Tae Chang

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  1. Young-Tae Chang
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The author declares no competing financial interests.

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Chang, YT. Small-molecule switch for zebrafish gene expression. Nat Chem Biol 3, 135–136 (2007). https://doi.org/10.1038/nchembio0307-135

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  • DOI: https://doi.org/10.1038/nchembio0307-135

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