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Probing cellular systems with chemistry

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Chemical and genetic approaches are extensively used to probe living systems at the subcellular level and to advance therapeutic target discovery. The 2006 American Society for Cell Biology meeting highlighted the growing importance of chemical biology approaches in cell biology research.

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Figure 1
Figure 2: Small molecules used for exploring biology and for therapeutic target discovery.

References

  1. Mayer, T.U. et al. Science 286, 971–974 (1999).

    Article  CAS  Google Scholar 

  2. Peters, U., Cherian, J., Kim, J.H., Kwok, B.H. & Kapoor, T.M. Nat. Chem. Biol. 2, 618–626 (2006).

    Article  CAS  Google Scholar 

  3. De Toledo, M. et al. FEBS Lett. 480, 287–292 (2000).

    Article  CAS  Google Scholar 

  4. Blangy, A. et al. Biol. Cell 98, 511–522 (2006).

    Article  CAS  Google Scholar 

  5. Blangy, A. et al. J. Cell Sci. 113, 729–739 (2000).

    CAS  PubMed  Google Scholar 

  6. Li, L. et al. Science 305, 1471–1474 (2004).

    Article  CAS  Google Scholar 

  7. Knight, Z.A. et al. Cell 125, 733–747 (2006).

    Article  CAS  Google Scholar 

  8. Fan, Q.W. et al. Cancer Cell 9, 341–349 (2006).

    Article  CAS  Google Scholar 

  9. Toth, B. et al. J. Biol. Chem. 281, 36369–36377 (2006).

    Article  CAS  Google Scholar 

  10. Kaehr, B. et al. Anal. Chem. 78, 3198–3202 (2006).

    Article  CAS  Google Scholar 

  11. Kaehr, B., Allen, R., Javier, D.J., Currie, J. & Shear, J.B. Proc. Natl. Acad. Sci. USA 101, 16104–16108 (2004).

    Article  CAS  Google Scholar 

  12. Kaehr, B. & Shear, J.B. J. Am. Chem. Soc. (in the press).

  13. Griffin, B.A., Adams, S.R. & Tsien, R.Y. Science 281, 269–272 (1998).

    Article  CAS  Google Scholar 

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Hannoush, R. Probing cellular systems with chemistry. Nat Chem Biol 3, 131–134 (2007). https://doi.org/10.1038/nchembio0307-131

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  • DOI: https://doi.org/10.1038/nchembio0307-131

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