Skip to main content

Advertisement

Log in

Metabolomics cuts to the chase to chase the cuts

  • News & Views
  • Published:

From Nature Chemical Biology

View current issue Submit your manuscript

Peptidases are enzymes that trim small protein fragments called peptides to regulate their biological functions. A new method opens the door to chasing down and identifying important cutting events mediated by peptidases involved in metabolic regulation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Metabolomic identification of downstream substrates of DPP4.

Kim Caesar

References

  1. Quesada, V., Ordonez, G.R., Sanchez, L.M., Puente, X.S. & Lopez-Otin, C. Nucleic Acids Res. published online, doi:10.1093/nar/gkn570 (6 September 2008).

  2. Rawlings, N.D., Morton, F.R., Kok, C.Y., Kong, J. & Barrett, A.J. Nucleic Acids Res. 36, D320–D325 (2008).

    Article  CAS  Google Scholar 

  3. Tagore, D.M. et al. Nat. Chem. Biol. 5, 23–25 (2009).

    Article  CAS  Google Scholar 

  4. Holst, J.J. Physiol. Rev. 87, 1409–1439 (2007).

    Article  CAS  Google Scholar 

  5. Deacon, C.F., Carr, R.D. & Holst, J.J. Front. Biosci. 13, 1780–1794 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bogyo, M. Metabolomics cuts to the chase to chase the cuts. Nat Chem Biol 5, 5–6 (2009). https://doi.org/10.1038/nchembio0109-5

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio0109-5

  • Springer Nature America, Inc.

Navigation