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Blocking galactolipid biosynthesis

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The first selective inhibitor of monogalactosyldiacylglycerol (MGDG) synthase was identified from a chemical library screen. The competitive inhibitor effectively targets MGDG concentrations across plant tissues and was used to demonstrate a new role for galactolipids in pollen-tube development.

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Figure 1: Identification of an inhibitor of MGDG synthases.

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Authors and Affiliations

  1. Department of Biological Sciences, Kent D. Chapman is at the Center for Plant Lipid Research, University of North Texas, Denton, Texas, USA.,

    Kent D Chapman

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  1. Kent D Chapman
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Correspondence to Kent D Chapman.

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The author declares no competing financial interests.

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Chapman, K. Blocking galactolipid biosynthesis. Nat Chem Biol 7, 761–762 (2011). https://doi.org/10.1038/nchembio.691

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