Many nuclear and cytoplasmic proteins are post-translationally modified by both O-GlcNAc and phosphate, but determining whether a single copy of a protein bears multiple modifications remains a challenge. A new analytic approach reveals a surprising correlation between phosphorylation and the O-GlcNAc modification.
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Kohler, J. A shift for the O-GlcNAc paradigm. Nat Chem Biol 6, 634–635 (2010). https://doi.org/10.1038/nchembio.429
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DOI: https://doi.org/10.1038/nchembio.429
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