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Screening

Your brain on drugs

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Manipulation of stem cells is an important therapeutic goal that has proven difficult to achieve. A recent report describes a novel in vivo small-molecule screen and identifies a modulator of mammalian neurogenesis that partially reverses age-related declines in cognition.

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Figure 1: An in vivo screen for proneurogenic small molecules.

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Correspondence to Jonathan P Saxe.

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Saxe, J. Your brain on drugs. Nat Chem Biol 6, 639–640 (2010). https://doi.org/10.1038/nchembio.427

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