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Antibiotics

Inactive but not inert

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Antibiotics can break down through the action of enzymes or through non-enzymatic processes. In the case of tetracycline, this drug 'debris' can have unexpected biological activities, including selection against resistance.

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Figure 1: Antibiotic resistance is not neutral.

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Authors and Affiliations

  1. Department of Biochemistry and Biomedical Sciences, Gerard D. Wright is at the M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.,

    Gerard D Wright

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  1. Gerard D Wright
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Correspondence to Gerard D Wright.

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Wright, G. Inactive but not inert. Nat Chem Biol 6, 85–86 (2010). https://doi.org/10.1038/nchembio.299

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