Membrane curvature sensing by amphipathic helices is an emergent property of the ensemble of molecules and membrane sites. New data suggest that individual molecules do not experience stronger binding to curved membranes.
References
Zimmerberg, J. & Kozlov, M.M. Nat. Rev. Mol. Cell Biol. 7, 9–19 (2006).
Parthasarathy, R. & Groves, J.T. Soft Matter 3, 24–33 (2007).
Hatzakis, N.S. et al. Nat. Chem. Biol. 5, 835–841 (2009).
Peter, B.J. et al. Science 303, 495–499 (2004).
Drin, G. et al. Nat. Struct. Mol. Biol. 14, 138–146 (2007).
Nuscher, B. et al. J. Biol. Chem. 279, 21966–21975 (2004).
Yeung, T. et al. Science 319, 210–213 (2008).
McLaughlin, S. & Murray, D. Nature 438, 605–611 (2005).
Linder, M.E. & Deschenes, R.J. Nat. Rev. Mol. Cell Biol. 8, 74–84 (2007).
Rocks, O. et al. Science 307, 1746–1752 (2005).
Lemmon, M.A. Nat. Rev. Mol. Cell Biol. 9, 99–111 (2008).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Groves, J. The physical chemistry of membrane curvature. Nat Chem Biol 5, 783–784 (2009). https://doi.org/10.1038/nchembio.247
Issue Date:
DOI: https://doi.org/10.1038/nchembio.247
- Springer Nature America, Inc.
This article is cited by
-
Adhesion energy controls lipid binding-mediated endocytosis
Nature Communications (2024)