Skip to main content
SpringerLink
Log in

Structural biology

HDAC6 finally crystal clear

  • News & Views
  • Published:

From Nature Chemical Biology

View current issue Submit your manuscript

A Corrigendum to this article was published on 20 September 2016

This article has been updated

Crystal structures of both catalytic domains of HDAC6 provide insights into the mechanisms of deacetylation for their specific substrates and a structural basis for understanding selective inhibition of HDAC6.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: HDAC6 harbors a unique substrate-binding site.

Change history

  • 26 August 2016

    In the article originally published, the author omitted a reference describing the discovery of HDAC6. This reference is now included as reference 9. The error has been corrected in the HTML and PDF versions of the article.

References

  1. Hubbert, C. et al. Nature 417, 455–458 (2002).

    Article  CAS  Google Scholar 

  2. Kawaguchi, Y. et al. Cell 115, 727–738 (2003).

    Article  CAS  Google Scholar 

  3. Hai, Y. & Christianson, D.W. Nat. Chem. Biol. 12, 741–747 (2016).

    Article  CAS  Google Scholar 

  4. Miyake, Y. et al. Nat. Chem. Biol. 12, 748–754 (2016).

    Article  CAS  Google Scholar 

  5. Gregoretti, I.V., Lee, Y.M. & Goodson, H.V. J. Mol. Biol. 338, 17–31 (2004).

    Article  CAS  Google Scholar 

  6. Li, Y., Shin, D. & Kwon, S.H. FEBS J. 280, 775–793 (2013).

    CAS  PubMed  Google Scholar 

  7. Li, L. & Yang, X.J. Cell. Mol. Life Sci. 72, 4237–4255 (2015).

    Article  CAS  Google Scholar 

  8. Grozinger, C.M., Hassig, C.A. & Schreiber, S.L. Proc. Natl. Acad. Sci. USA 96, 4868–4873 (1999).

    Article  CAS  Google Scholar 

  9. Verdel, A. & Khochbin, S. J. Biol. Chem. 274, 2440–2445 (1999).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Yanli Liu is at the College of Life Sciences, Central China Normal University, Wuhan, China.,

    Yanli Liu

  2. Li Li is at the Structural Genomics Consortium and the Department of Physiology, University of Toronto, Toronto, Ontario, Canada.,

    Li Li

  3. and at the Structural Genomics Consortium and the Department of Physiology, Jinrong Min is at the College of Life Sciences, Central China Normal University, Wuhan, China, University of Toronto, Toronto, Ontario, Canada.,

    Jinrong Min

Authors
  1. Yanli Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Li Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jinrong Min
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jinrong Min.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Liu, Y., Li, L. & Min, J. HDAC6 finally crystal clear. Nat Chem Biol 12, 660–661 (2016). https://doi.org/10.1038/nchembio.2158

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio.2158

  • Springer Nature America, Inc.

This article is cited by

Search

Navigation