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Calprotectin and iron match up

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Iron availability plays a decisive role in host-pathogen interaction, and limitation of iron availability to microbes has been characterized as an effective host defense strategy. The identification of the iron-scavenging property of the neutrophil protein calprotectin adds an important new piece to this concept of nutritional immunity.

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Figure 1: Effects of calprotectin on bacterial proliferation.

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Correspondence to Guenter Weiss.

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Weiss, G. Calprotectin and iron match up. Nat Chem Biol 11, 756–757 (2015). https://doi.org/10.1038/nchembio.1915

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  • DOI: https://doi.org/10.1038/nchembio.1915

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