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Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases

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Figure 1: Inhibitory data of chaetocin (1) and analogs against SUV39H1.

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Acknowledgements

We would like to acknowledge Cancer Research UK for funding (grant C21484A6944).

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Authors and Affiliations

  1. Department of Chemistry, Imperial College London, London, UK

    Fanny L Cherblanc & Matthew J Fuchter

  2. Department of Surgery and Cancer, Mechanism and Functional Screening Facility, Imperial College London, London, UK

    Kathryn L Chapman

  3. Department of Surgery and Cancer, Ovarian Cancer Action Research Centre, Imperial College London, London, UK

    Robert Brown

Authors
  1. Fanny L Cherblanc
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  2. Kathryn L Chapman
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  3. Robert Brown
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  4. Matthew J Fuchter
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Correspondence to Matthew J Fuchter.

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Cherblanc, F., Chapman, K., Brown, R. et al. Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases. Nat Chem Biol 9, 136–137 (2013). https://doi.org/10.1038/nchembio.1187

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