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DNA nanotechnology

Bringing lipid bilayers into shape

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Lipid bilayers form the thin and floppy membranes that define the boundary of compartments such as cells. Now, a method to control the shape and size of bilayers using DNA nanoscaffolds has been developed. Such designer materials advance synthetic biology and could find use in membrane research.

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Figure 1: DNA nanoscaffolds template bilayer vesicles of tunable size and morphology.

References

  1. Zhang, Z., Yang, Y., Pincet, F., Llaguno, M. C. & Lin, C. Nat. Chem. 9, 653–659 (2017).

    Article  CAS  Google Scholar 

  2. Chen, Y. J., Groves, B., Muscat, R. A. & Seelig, G. Nat. Nanotech. 10, 748–760 (2015).

    Article  CAS  Google Scholar 

  3. Pinheiro, A. V., Han, D., Shih, W. M. & Yan, H. Nat. Nanotech. 6, 763–772 (2011).

    Article  CAS  Google Scholar 

  4. Czogalla, A. et al. Angew. Chem. Int. Ed. 54, 6501–6505 (2015).

    Article  CAS  Google Scholar 

  5. Kocabey, S. et al. ACS Nano 9, 3530–3539 (2015).

    Article  CAS  Google Scholar 

  6. Johnson-Buck, A., Jiang, S., Yan, H. & Walter, N. G. ACS Nano 8, 5641–5649 (2014).

    Article  CAS  Google Scholar 

  7. Langecker, M. et al. Science 338, 932–936 (2012).

    Article  CAS  Google Scholar 

  8. Gopfrich, K. et al. Nano Lett. 15, 3134–3138 (2015).

    Article  CAS  Google Scholar 

  9. Burns, J. R., Seifert, A., Fertig, N. & Howorka, S. Nat. Nanotech. 11, 152–156 (2016).

    Article  CAS  Google Scholar 

  10. Yang, Y. et al. Nat. Chem. 8, 476–483 (2016).

    Article  CAS  Google Scholar 

  11. Xu, W. et al. J. Am. Chem. Soc. 138, 4439–4447 (2016).

    Article  CAS  Google Scholar 

  12. Perrault, S. D. & Shih, W. M. ACS Nano 8, 5132–5140 (2014).

    Article  CAS  Google Scholar 

  13. Howorka, S. Science 352, 890–891 (2016).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Stefan Howorka is in the Department of Chemistry and the Institute of Structural and Molecular Biology, University College London, London WC1H 0AJ, UK,

    Stefan Howorka

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  1. Stefan Howorka
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Correspondence to Stefan Howorka.

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Howorka, S. Bringing lipid bilayers into shape. Nature Chem 9, 611–613 (2017). https://doi.org/10.1038/nchem.2809

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