Skip to main content
SpringerLink
Log in

Organometallic chemistry

A shortcut to molecular complexity

  • News & Views
  • Published:

From Nature Chemistry

View current issue Submit your manuscript

A unique transformation for the site-selective cleavage of one C–C single bond and two C–H bonds in sequence has now been developed. This enables a simple carbon skeleton to be reorganized into a significantly more complex form with remarkable efficiency.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Catalytic cycle proposed by Lautens and co-workers.

References

  1. Bruce, M. I. Angew. Chem. Int. Ed. 16, 73–86 (1977).

    Article  Google Scholar 

  2. Webster, D. E. Adv. Organomet. Chem. 15, 147–188 (1977).

    Article  CAS  Google Scholar 

  3. Shilov, A. E., Steinman, A. A. Coord. Chem. Rev. 24, 97–143 (1977).

    Article  CAS  Google Scholar 

  4. Crabtree, R. H. Chem. Rev. 85, 245–269 (1985).

    Article  CAS  Google Scholar 

  5. Murai, S. et al. Nature 366, 529–531 (1993).

    Article  CAS  Google Scholar 

  6. Hartwig, J. J. Am. Chem. Soc. 138, 2–24 (2016).

    Article  CAS  Google Scholar 

  7. Murakami, M. et. al. in Cleavage of Carbon–Carbon Single Bonds by Transition Metals (eds Murakami, M. & Chatani, N.) (Wiley-VCH, 2015).

  8. Ye, J. et. al. Nat. Chem. 9, 361–368 (2017).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Masahiro Murakami and Naoki Ishida are in the Department of Synthetic Chemistry and Biological Chemistry at Kyoto University, Katsura, Kyoto 615-8510, Japan,

    Masahiro Murakami & Naoki Ishida

Authors
  1. Masahiro Murakami
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Naoki Ishida
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Masahiro Murakami.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Murakami, M., Ishida, N. A shortcut to molecular complexity. Nature Chem 9, 298–299 (2017). https://doi.org/10.1038/nchem.2750

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchem.2750

  • Springer Nature Limited

This article is cited by

Search

Navigation