Sensing neuronal activity using fluorescence has many potential advantages over current methods. Now, by taking advantage of photoinduced electron transfer, fluorescent sensors have been developed that allow high-fidelity recording of neural signals in real time.
References
Miller, E. W. et al. Proc. Natl Acad. Sci. USA 109, 2114–2119 (2012).
Davis, W. B., Svec, W. A., Ratner, M. A. & Wasielewski, M. R. Nature 396, 60–63 (1998).
Balzani, V. (ed.) Electron Transfer in Chemistry (Wiley-VCH, 2001).
de Silva, A. P. et al. Angew. Chem. Int. Ed. Engl. 34, 1728–1731 (1995).
de Silva, A. P. J. Phys. Chem. Lett. 2, 2865–2872 (2011).
Ueno, T. & Nagano, T. Nature Meth. 8, 642–645 (2011).
Okabe, K. et al. Nature Commun. 3, 705–714 (2012).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
de Silva, A. Bright ideas. Nature Chem 4, 440–441 (2012). https://doi.org/10.1038/nchem.1360
Published:
Issue Date:
DOI: https://doi.org/10.1038/nchem.1360
- Springer Nature Limited
This article is cited by
-
A Simple and Selective Fluorescent Sensor for Zn2+ and H+ Ions in Aqueous Solution with OR Logic Gate Function
Journal of Fluorescence (2016)