The scope of dynamic combinatorial chemistry is somewhat limited by the small number of predictably reversible reactions. Now, secondary alcohols are shown to quickly and reversibly react with iminium ions to form hemiaminal ethers, opening up opportunites for their use in the construction of complex — and functional — dynamic architectures.
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Miljanić, O. Alcohols in the mix. Nature Chem 3, 909–910 (2011). https://doi.org/10.1038/nchem.1203
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DOI: https://doi.org/10.1038/nchem.1203
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