Skip to main content

Advertisement

Log in

The skinny on obesity and cancer

  • News & Views
  • Published:

From Nature Cell Biology

View current issue Submit your manuscript

Obesity now rivals smoking as one of the leading preventable causes of cancer. Obesity-associated neutrophilia is now shown to enhance breast cancer metastasis and to be reversible through dietary modification and weight loss.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: The effects of obesity and weight loss on breast cancer metastasis.

References

  1. Calle, E. E. & Kaaks, R. Nat. Rev. Cancer 4, 579–591 (2004).

    Article  CAS  Google Scholar 

  2. Ligibel, J. A. et al. J. Clin. Oncol. 32, 3568–3574 (2014).

    Article  Google Scholar 

  3. Coussens, L. M., Zitvogel, L. & Palucka, A. K. Science 339, 286–291 (2013).

    Article  CAS  Google Scholar 

  4. McAllister, S. S. & Weinberg, R. A. Nat. Cell Biol. 16, 717–727 (2014).

    Article  CAS  Google Scholar 

  5. Peinado, H. et al. Nat. Rev. Cancer 17, 302–317 (2017).

    Article  CAS  Google Scholar 

  6. Quail, D. F. et al. Nat. Cell Biol. 19, 974–987 (2017).

    Article  CAS  Google Scholar 

  7. Osman, M. A. & Hennessy, B. T. Clin. Med. Insights Oncol. 9, 105–112 (2015).

    Article  Google Scholar 

  8. Weigelt, B., Peterse, J. L. & van 't Veer, L. J. B Nat. Rev. Cancer 5, 591–602 (2005).

    Article  CAS  Google Scholar 

  9. Zhang, Y. et al. Nature 372, 425–432 (1994).

    Article  CAS  Google Scholar 

  10. Alemán, J. O. et al. J. Endocr. Soc. 1, 625–637 (2017).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sandra S. McAllister.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sceneay, J., McAllister, S. The skinny on obesity and cancer. Nat Cell Biol 19, 887–888 (2017). https://doi.org/10.1038/ncb3583

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncb3583

  • Springer Nature Limited

This article is cited by

Navigation