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Actin puts the squeeze on Drosophila glue secretion

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An Erratum to this article was published on 25 February 2016

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An actin filament coat promotes cargo expulsion from large exocytosing vesicles, but the mechanisms of coat formation and force generation have been poorly characterized. Elegant imaging studies of the Drosophila melanogaster salivary gland now reveal how actin and myosin are recruited, and show that myosin II forms a contractile 'cage' that facilitates exocytosis.

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Figure 1: Exocytosis of glue granules in the Drosophila salivary gland.

Change history

  • 04 February 2016

    In the version of this News and Views article originally published, the author's affiliation was incorrect. This was corrected online on 4 February 2016.

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Authors and Affiliations

  1. Christien J. Merrifield is at the Institute for Integrative Biology of the Cell, Bât. 34, Avenue de la Terrasse, 9198 Gif sur Yvette Cedex, France,

    Christien J. Merrifield

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  1. Christien J. Merrifield
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Correspondence to Christien J. Merrifield.

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Merrifield, C. Actin puts the squeeze on Drosophila glue secretion. Nat Cell Biol 18, 142–144 (2016). https://doi.org/10.1038/ncb3305

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