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Organizing cytoplasmic microtubules: no nucleus, no problem

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Correct organization of a polarised microtubule array is vital for eukaryotic cells. Microtubule organizing centers (MTOCs) are generally believed to have an essential role in this process. However, two papers published in this issue have demonstrated that in fission yeast, interphase microtubules can self-organize in anucleate cells lacking any authentic MTOC.

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Figure 1: Microtubule organizing centers in fission yeast and generation of anucleate cells.
Figure 2: Schematic representation of microtubule organization of a normal cell and an anucleate cell.

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Authors and Affiliations

  1. Tetsuya Horio is in the Institute of Health Biosciences, University of Tokushima Graduate School, Tokushima, 770-8503, Japan

    Tetsuya Horio

  2. Takashi Toda is in the Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK

    Takashi Toda

Authors
  1. Tetsuya Horio
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  2. Takashi Toda
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Horio, T., Toda, T. Organizing cytoplasmic microtubules: no nucleus, no problem. Nat Cell Biol 8, 1041–1043 (2006). https://doi.org/10.1038/ncb1006-1041

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